Hantavirus :

Black Rat pic by TEN

As per the recent study in Madagascar Black Rat was identified as the exclusive carrier of the Hantavirus .. Hantavirus refers to a group of viruses carried mainly by rodents that can cause various diseases in humans .

Transmission:

  • Hantavirus is primarily transmitted to humans through contact with infected rodents .
  • People can contract the virus by inhaling air contaminated with aerosolized virus from rodent urine, droppings, or saliva .
  • Other less common routes of transmission include touching contaminated surfaces and then touching the face, eating contaminated food, or, rarely, through rodent bites .

Diseases Caused by Hantavirus:

Hantaviruses can cause different syndromes, with the two most common being :

  • Hantavirus Pulmonary Syndrome (HPS): Primarily found in the Americas, HPS affects the lungs and can be fatal .
  • Hemorrhagic Fever with Renal Syndrome (HFRS): Found in Europe and Asia, HFRS affects the kidneys and can also lead to severe health issues .

Symptoms:

Symptoms of hantavirus infection can appear between 1 to 8 weeks after exposure and often progress over days or weeks .

  • Early symptoms are often flu-like and can include :
    • Fever
    • Fatigue
    • Muscle aches
    • Headache
    • Dizziness
    • Chills
    • Nausea and vomiting
    • Abdominal pain
    • Diarrhea
  • Later symptoms of HPS can include :
    • Coughing
    • Shortness of breath
    • Rapid heart rate
    • Fluid buildup in the lungs (pulmonary edema)
  • Later symptoms of HFRS can include :
    • Shock
    • Low blood pressure
    • Vascular leakage
    • Kidney failure
    • Low platelet count

Diagnosis:

  • Early diagnosis is crucial for effective management .
  • Diagnosis involves a physical examination, a review of symptoms, and questions about potential rodent exposure .
  • An enzyme-linked immunosorbent assay (ELISA) blood test can confirm the presence of hantavirus .
  • Additional tests, such as chest X-rays and complete blood counts, may be conducted to assess the severity and impact on the lungs and other organs .

Treatment:

  • There is no specific cure for hantavirus infection; treatment focuses on managing symptoms and providing supportive care .
  • Treatment may include :
    • Oxygen therapy
    • Mechanical ventilation
    • Medications to manage blood pressure
    • In severe cases, extracorporeal membrane oxygenation (ECMO)
    • Hemodialysis for HFRS to support kidney function
  • Some antiviral medications, like ribavirin, have shown potential in treating certain hantavirus strains if administered early in the course of infection, but more research is needed .

Prevention:

  • The best way to prevent hantavirus infection is to avoid contact with rodents and their droppings, urine, and nesting materials .
  • Preventative measures include :
    • Sealing potential rodent entryways into buildings
    • Setting traps to control rodent populations
    • Using appropriate disinfectants when cleaning areas contaminated by rodents
    • Wearing protective gear, such as gloves and masks, when cleaning rodent-infested areas
    • Practicing good hygiene, such as frequent handwashing, especially after outdoor activities or potential contact with rodents
    • Properly storing food and disposing of waste to avoid attracting rodents

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